Symptoms And Diagnosis Of Ms - 983 Words

MS is traditionally described as clinical symptoms or signs of two CNS lesions separated in time and space that are not caused by other CNS disease. Due to the absence of a specific immune-based assay, the diagnosis of MS continues to be predicated on the clinical history and neurological examination; that is, finding multiple lesions in time and space in the CNS. Magnetic resonance imaging (MRI) remains the most important diagnostic tool for allowing the early and more precise diagnosis of the disease. Revised diagnostic criteria classify individuals in the categories of MS into either not multiple sclerosis or possible MS based on evidence from MRI (McDonald, 2001). Cerebrospinal fluid (CSF) examination allows the identification of oligoclonal immunoglobulin G (IgG) bands which are present in 98% of patients but can be absent in early disease. Also, approximately 80-90% of patients with MS have delayed visual evoked potentials (mainly optic neuritis). Finally, although there is no specific blood test for MS, the absence of other autoimmune markers (anti-nuclear antibodies, extractable nuclear antigen, anti-neutrophil cytoplasmic antibodies, anti-double-stranded DNA antibodies and anti-phospholipid antibodies) can be helpful. Criteria that determine â€Å"MS† have been revised several times in the last few years (2001, 2005, and 2010) (Polman, 2011). Criteria now enable diagnosis of MS when new MRI lesions define separation in time and space i.e., a new MRI lesion more than 30Show MoreRelatedDiagnosis Of Multiple Sclerosis ( Ms ) Essay1300 Words   |  6 PagesMultiple sclerosis (MS) is the most common inflammatory demyelinating disease of the CNS and the most frequent cause of nontraumatic neurological disability in young and middle-aged adults (1). Women are twice as likely to be affected as men, and onset typically occurs between the ages of 20 and 40 years (2). The diagnosis Depend on a detailed history; careful neurological examination; and supportive paraclinical investigations. According to the new McDonald criteria, the diagnosis of MS requires objectiveRead MoreMultiple Sclerosis : A Degenerative Disease Of The Central Nervous System1210 Words   |  5 Pagesdeterioration of the nerve it self. Multiple sclerosis, often referred to as MS, is called â€Å"multiple† for the many areas of the brain that are affected and â€Å"sclerosis† for the scarring of tissue and lesions that form on the brain and spinal cord. The symptoms of MS can vary significantly from one person to another depending on what area of the central nervous system the lesions are present. Some of the most common symptoms are blurring vision, loss of vision, fatigue, numbness and tingling, tremorsRead MoreA Short Note On The Loss Of Myelin Essay1214 Words   |  5 Pages Introduction: Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (brain and spinal cord). (3) MS is an inflammatory demyelinating condition. This means it is caused by damage to myelin – a fatty material that insulates nerves, acting much like the covering of an electric wire. Myelin allows a nerve to transmit its impulses rapidly. It is the speed and efficiency with which these impulses are conducted that permits smooth, rapid and coordinated movements toRead MoreSymptoms And Symptoms Of Schizophrenia1055 Words   |  5 Pagesconsidering all the signs and symptoms presented by the patient, Ms. Neighbors meets the DSM-5 diagnostic criteria for schizophreniform disorder. 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The principles of beneficence, non-maleficence and justice, the implications of their application to pain management, and the illness disease dichotomy in relation to non-organic pain will be considered in relationship to the case of Ms CP and management of her medically unexplained pain. A 28 year old female, Ms CP, presented to the Emergency Department complaining of abdominal painRead MoreThe Myelin Sheath And Its Effects On The Human Body1205 Words   |  5 PagesIntroduction Multiple Sclerosis, or MS, is a disease where the immune system attacks the myelin sheath surrounding axons of neurons in the Central Nervous System (CNS). In severe cases, Multiple Sclerosis can break down the nerves themselves. This leads to communication problems within the brain and between the brain and the rest of the body (Mayo Clinic.) The myelin sheath is an insulator- it surrounds and nourishes the axons. Exposing small points called the Nodes of Ranvier. The combinationRead MoreSymptoms And Treatment Of Nervous System Disorders917 Words   |  4 Pagesmade up of the brain and spinal cord. â€Å"In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause the nerves themselves to deteriorate or become permanently damaged.† (mayoclinic.org, by mayo clinic staff, Oct. 1, 2015) Knowing the symptoms of MS for early diagnoses is crucial when treating this disease. Symptoms can start mild so sometimes it isn’t caughtRead MoreMultiple Sclerosis Affects More People Than Most Would Think1098 Words   |  5 PagesMultiple Sclerosis affects more people than most would think. MS is an unpredictable disease that attacks the central nervous system but it is a difficult disease to diagnose due to multiple unknown factors. Each diagnosed case of MS is unique depending upon factors given by the patient. Understanding the different courses of Multiple Sclerosis, early diagnosis and the treatments of the disease all play an important role in bringing awareness of MS. Learning about Multiple Sclerosis can bring opportunities